Laboratory testing for antiphospholipid syndrome
نویسندگان
چکیده
منابع مشابه
Laboratory Diagnostics of Antiphospholipid Syndrome.
Diagnosis of antiphospholipid syndrome (APS) lies in the recognition of antiphospholipid antibodies (aPL). As standardization of tests for the detection of aPL is far from being optimal and reference material is not available, inappropriate diagnoses of APS are not unusual. In the last few years, the concept of triple test positivity has emerged as a useful tool to identify patients with APS. C...
متن کاملReview: Laboratory Evaluation of the Antiphospholipid Syndrome
Th e antiphospholipid syndrome (APS) was fi rst described in 1986. Th e original association of this hypercoagulable state with anticardiolipin antibodies (aCL) resulted from the synthesis of evidence stemming from laboratory fi ndings in systemic lupus erythematosus (SLE), ie, the frequent occurrence of false-positive VDRL tests and the paradoxical observation of the so-called “lupus anticoagu...
متن کاملAntiphospholipid syndrome: association between laboratory tests and clinical practice.
Antiphospholipid antibodies are a wide and heterogeneous group of immunoglobulins, whose presence inpatients with arterial and venous thrombosis, and obstetrical complications defines the antiphospholipid syndrome. We systematically reviewed published articles on this syndrome to investigate the association between thrombosis and the most common antiphospholipid antibodies. Lupus anticoagulants...
متن کاملLaboratory detection of the antiphospholipid syndrome via calibrated automated thrombography.
Lupus anticoagulants (LAC) consist of antiphospholipid antibodies, detected via their anticoagulant properties in vitro. Strong LAC relate to thromboembolic events, a hallmark of the antiphospholipid syndrome. We have analyzed whether detection of this syndrome would benefit from thrombin generation measurements. Therefore, calibrated automated thrombography was done in normal plasma (n = 30) a...
متن کاملAnticardiolipin syndrome: antiphospholipid syndrome.
North Am 2000;26:215–27. 14 Savill J. Recognition and phagocytosis of cells undergoing apoptosis. Br Med Bull 1997;53:491–508. 15 Elkon KB. Apoptosis in SLE – too little or too much? Review. Clin Exp Rheumatol 1994;12:553–9. 16 Drappa J, Vaishnaw AK, Sullivan KE, Chu JL, Elkon KB. Fas gene-mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmu...
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ژورنال
عنوان ژورنال: International Journal of Laboratory Hematology
سال: 2016
ISSN: 1751-5521
DOI: 10.1111/ijlh.12507